Joan Girardi has begun acting a little strange since her family moved to the city of Arcadia. No one knows that various people keep introducing themselves as God, and then giving the teenager specific directions to do things. Unsure of what God wants, and if she's even sane, Joan tentatively begins to follow God's cryptic directives, all the while trying to retain a "normal" teen-aged existence.

Amber Tamblyn
Joan Girardi

Joe Mantegna
Will Girardi

Mary Steenburgen
Helen Girardi

Jason Ritter
Kevin Girardi

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Michael Welch
Luke Girardi
When the hospitalized Joan is diagnosed with Lyme disease, she begins to question if she's been seeing God or merely experiencing the hallucinations that can be symptomatic of her condition... Upon hearing that Joan may have been suffering from the symptoms of Lyme Disease for months, a somewhat relieved Will and Helen believe this news may explain Joan's mood swings and atypical behavior, while a concerned Adam wonders if Joan will be different upon her recovery. Meanwhile, the hospitalized Joan experiences a crisis of faith -- and considers revealing to someone close to her that she's been talking to God. In separate circumstances, Helen and Will begin to rethink their belief systems after, respectively, experiencing spiritual dreams and miraculous events.
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